Sarcoidosis is a rare condition in which groups of immune cells form lumps, called granulomas, in various organs in the body. Inflammation, which may be triggered by infection or exposure to certain substances, is thought to play a role in the formation of granulomas.
Sarcoidosis can affect any organ. Most often it affects the lungs and lymph nodes in the chest. You may experience fatigue, which is extreme tiredness, or fever, but you may also experience other signs and symptoms depending on the organ that is affected. Your doctor will diagnose sarcoidosis in part by ruling out other diseases that have similar symptoms.
Determining whether treatment is needed and what type depends on your signs and symptoms, which organs are affected, and how well those organs are working. Medicines used to treat sarcoidosis help reduce inflammation or suppress the immune system. Many people recover with few or no long-term problems. Sometimes the disease causes permanent scarring in the affected organs. When scarring happens in the lungs, this is called pulmonary fibrosis.